Efficient human breast cancer xenograft regression after a single treatment with a novel liposomal formulation of epirubicin prepared using the EDTA ion gradient method.

Efficient human breast cancer xenograft regression after a single treatment with a novel liposomal formulation of epirubicin prepared using the EDTA ion gradient method.

Liposomes act as efficient drug carriers. Recently, epirubicin (EPI) formulation was developed using a novel EDTA ion gradient method for drug encapsulation. This formulation displayed very good stability and drug retention in vitro in a two-year long-term stability experiment. The cryo-TEM images s...

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Bibliographic Details
Main Authors: Jerzy Gubernator, Dominik Lipka, Mariola Korycińska, Katarzyna Kempińska, Magdalena Milczarek, Joanna Wietrzyk, Rafał Hrynyk, Sabine Barnert, Regine Süss, Arkadiusz Kozubek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24621591/?tool=EBI

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