Reactive Oxygen Species Generation in Human Cells by a Novel Magnetic Resonance Imaging Contrast Agent

The novel positive-contrast magnetic resonance imaging (MRI) marker C4 consists of an aqueous solution of cobalt chloride (CoCl2) complexed with the chelator N-acetylcysteine (NAC). We evaluated whether the presence of C4 or its components would produce reactive oxygen species (ROS, including hydrox...

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Bibliographic Details
Main Authors: Li Wang, Eric Lin, Mary J. Johansen, Timothy Madden, Edward Felix, Karen S. Martirosyan, Steven J. Frank
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2018/6362426

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