Self-Seeding Microwells to Isolate and Assess the Viability of Single Circulating Tumor Cells

The availability of viable tumor cells could significantly improve the disease management of cancer patients. Here we developed and evaluated a method using self-seeding microwells to obtain single circulating tumor cells (CTC) and assess their potential to expand. Conditions were optimized using ce...

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Bibliographic Details
Main Authors: Kiki C. Andree, Fikri Abali, Lisa Oomens, Fiona R. Passanha, Joska J. Broekmaat, Jaco Kraan, Pauline A.J. Mendelaar, Stefan Sleijfer, Leon W.M.M. Terstappen
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
CTC
Online Access:https://www.mdpi.com/1422-0067/20/3/477