Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer

Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer

The mechanisms through which cancer cells lock in altered transcriptional programs in support of metastasis remain largely unknown. Through integrative analysis of clinical breast cancer gene expression datasets, cell line models of breast cancer progression, and mutation data from cancer genome res...

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Bibliographic Details
Main Authors: Sakari Vanharanta, Christina B Marney, Weiping Shu, Manuel Valiente, Yilong Zou, Aldo Mele, Robert B Darnell, Joan Massagué
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-06-01
Series:eLife
Subjects:
metastasis
RNA binding protein
breast cancer
Online Access:https://elifesciences.org/articles/02734

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