The viral chemokine MCK-2 of murine cytomegalovirus promotes infection as part of a gH/gL/MCK-2 complex.

The viral chemokine MCK-2 of murine cytomegalovirus promotes infection as part of a gH/gL/MCK-2 complex.

Human cytomegalovirus (HCMV) forms two gH/gL glycoprotein complexes, gH/gL/gO and gH/gL/pUL(128,130,131A), which determine the tropism, the entry pathways and the mode of spread of the virus. For murine cytomegalovirus (MCMV), which serves as a model for HCMV, a gH/gL/gO complex functionally homolog...

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Main Authors: Felicia M Wagner, Ilija Brizic, Adrian Prager, Tihana Trsan, Maja Arapovic, Niels A W Lemmermann, Jürgen Podlech, Matthias J Reddehase, Frederic Lemnitzer, Jens Bernhard Bosse, Martina Gimpfl, Lisa Marcinowski, Margaret MacDonald, Heiko Adler, Ulrich H Koszinowski, Barbara Adler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23935483/?tool=EBI

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