Brain-derived neurotrophic factor/FK506-binding protein 5 genotype by childhood trauma interactions do not impact on hippocampal volume and cognitive performance.

Brain-derived neurotrophic factor/FK506-binding protein 5 genotype by childhood trauma interactions do not impact on hippocampal volume and cognitive performance.

In the development of psychotic symptoms, environmental and genetic factors may both play a role. The reported association between childhood trauma and psychotic symptoms could therefore be moderated by single nucleotide polymorphisms (SNPs) associated with the stress response, such as FK506-binding...

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Bibliographic Details
Main Authors: Dennis Hernaus, Ruud van Winkel, Ed Gronenschild, Petra Habets, Gunter Kenis, Machteld Marcelis, Jim van Os, Inez Myin-Germeys, Dina Collip, for Genetic Risk and Outcome in Psychosis (G.R.O.U.P.)
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24658422/?tool=EBI

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