Activation of human B cells by the agonist CD40 antibody CP-870,893 and augmentation with simultaneous toll-like receptor 9 stimulation

Activation of human B cells by the agonist CD40 antibody CP-870,893 and augmentation with simultaneous toll-like receptor 9 stimulation

<p>Abstract</p> <p>Background</p> <p>CD40 activation of antigen presenting cells (APC) such as dendritic cells (DC) and B cells plays an important role in immunological licensing of T cell immunity. Agonist CD40 antibodies have been previously shown in murine models to...

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Bibliographic Details
Main Authors: Rüter Jens, Mick Rosemarie, Carpenter Erica L, Vonderheide Robert H
Format: Article
Language:English
Published: BMC 2009-11-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/7/1/93

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