A(H5N1) Virus Evolution in South East Asia

A(H5N1) Virus Evolution in South East Asia

Highly Pathogenic Avian Influenza (HPAI) H5N1 virus is an ongoing public health and socio-economic challenge, particularly in South East Asia. H5N1 is now endemic in poultry in many countries, and represents a major pandemic threat. Here, we describe the evolution of H5N1 virus in South East Asia, t...

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Main Authors: Philippe Buchy, Srey Viseth Horm, Ramona Alikiiteaga Gutiérrez, Monica Jane Naughtin, Sorn San
Format: Article
Language:English
Published: MDPI AG 2009-10-01
Series:Viruses
Subjects:
avian influenza
H5N1 virus
evolution
South East Asia
Online Access:http://www.mdpi.com/1999-4915/1/3/335/
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spelling doaj-6eb47aa269a349dd80dd77d10dd86d0e2020-11-24T22:57:32ZengMDPI AGViruses1999-49152009-10-011333536110.3390/v1030335A(H5N1) Virus Evolution in South East AsiaPhilippe BuchySrey Viseth HormRamona Alikiiteaga GutiérrezMonica Jane NaughtinSorn SanHighly Pathogenic Avian Influenza (HPAI) H5N1 virus is an ongoing public health and socio-economic challenge, particularly in South East Asia. H5N1 is now endemic in poultry in many countries, and represents a major pandemic threat. Here, we describe the evolution of H5N1 virus in South East Asia, the reassortment events leading to high genetic diversity in the region, and factors responsible for virus spread. The virus has evolved with genetic variations affecting virulence, drug-resistance, and adaptation to new host species. The constant surveillance of these changes is of primary importance in the global efforts of the scientific community. http://www.mdpi.com/1999-4915/1/3/335/avian influenzaH5N1 virusevolutionSouth East Asia
collection DOAJ
language English
format Article
sources DOAJ
author Philippe Buchy
Srey Viseth Horm
Ramona Alikiiteaga Gutiérrez
Monica Jane Naughtin
Sorn San
spellingShingle Philippe Buchy
Srey Viseth Horm
Ramona Alikiiteaga Gutiérrez
Monica Jane Naughtin
Sorn San
A(H5N1) Virus Evolution in South East Asia
Viruses
avian influenza
H5N1 virus
evolution
South East Asia
author_facet Philippe Buchy
Srey Viseth Horm
Ramona Alikiiteaga Gutiérrez
Monica Jane Naughtin
Sorn San
author_sort Philippe Buchy
title A(H5N1) Virus Evolution in South East Asia
title_short A(H5N1) Virus Evolution in South East Asia
title_full A(H5N1) Virus Evolution in South East Asia
title_fullStr A(H5N1) Virus Evolution in South East Asia
title_full_unstemmed A(H5N1) Virus Evolution in South East Asia
title_sort a(h5n1) virus evolution in south east asia
publisher MDPI AG
series Viruses
issn 1999-4915
publishDate 2009-10-01
description Highly Pathogenic Avian Influenza (HPAI) H5N1 virus is an ongoing public health and socio-economic challenge, particularly in South East Asia. H5N1 is now endemic in poultry in many countries, and represents a major pandemic threat. Here, we describe the evolution of H5N1 virus in South East Asia, the reassortment events leading to high genetic diversity in the region, and factors responsible for virus spread. The virus has evolved with genetic variations affecting virulence, drug-resistance, and adaptation to new host species. The constant surveillance of these changes is of primary importance in the global efforts of the scientific community.
topic avian influenza
H5N1 virus
evolution
South East Asia
url http://www.mdpi.com/1999-4915/1/3/335/
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AT ramonaalikiiteagagutierrez ah5n1virusevolutioninsoutheastasia
AT monicajanenaughtin ah5n1virusevolutioninsoutheastasia
AT sornsan ah5n1virusevolutioninsoutheastasia
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