Simulating CXCR5 Dynamics in Complex Tissue Microenvironments
To effectively navigate complex tissue microenvironments, immune cells sense molecular concentration gradients using G-protein coupled receptors. However, due to the complexity of receptor activity, and the multimodal nature of chemokine gradients in vivo, chemokine receptor activity in situ is poor...
Main Authors: | Jason Cosgrove, Kieran Alden, Jens V. Stein, Mark C. Coles, Jon Timmis |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-09-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2021.703088/full |
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