| Summary: | Abstract: A 2-year-old sheep presented with complains of nasal discharge and respiratory distress from a flock consisting 125 animals. Owner stated that the ewe started having clear nasal discharge more than three months and 15 sheep died with similar clinical symptoms in 3 years of period. During the clinical examination, depression and inappetence were observed to the sheep. Because of poor prognosis the ewe was euthanatized. At necropsy, bilateral tumors were seen in nasal cavity. Masses were soft, pinkish color, covered by mucinous exudate and completely filled the nasal cavity, invasion to the nasal sinuses were observed. The tumors localized in the right and left side of nasal cavity were 4,5x4x2 cm and 9,5x10x4 cm in diameters respectively. At the histopathological examination, the mass consisted of well-differentiated cuboidal to columnar cells with moderate amount of eosinophilic cytoplasm and round to oval nuclei. According to clinical and pathological findings the mass diagnosed as Enzootic Nasal Adenocarcinoma. This is the first Enzootic Nasal Adenocarcinoma report in a sheep in Turkey.
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