Indoxyl Sulfate—Review of Toxicity and Therapeutic Strategies
Indoxyl sulfate is an extensively studied uremic solute. It is a small molecule that is more than 90% bound to plasma proteins. Indoxyl sulfate is derived from the breakdown of tryptophan by colon microbes. The kidneys achieve high clearances of indoxyl sulfate by tubular secretion, a function not r...
Main Authors: | Sheldon C. Leong, Tammy L. Sirich |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-11-01
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Series: | Toxins |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6651/8/12/358 |
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