Persistence of different forms of transient RNAi during apoptosis in mammalian cells.

Gene silencing by transient or stable RNA-interference (RNAi) is used for the study of apoptosis with an assumption that apoptotic events will not influence RNAi. However, we recently reported that stable RNAi, i.e., a permanent gene-knockdown mediated by shRNA-generating DNA vectors that are integr...

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Bibliographic Details
Main Authors: Febitha Kandan-Kulangara, Rashmi G Shah, El Bachir Affar, Girish M Shah
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2923616?pdf=render