Preoperative Parathyroid Needle Localization: A Minimally Invasive Novel Technique in Reoperative Settings

Background. Reoperative parathyroid surgery for primary hyperparathyroidism can be challenging. Numerous preoperative localization techniques have been employed to facilitate a more focused surgical exploration. This paper describes a novel, minimally invasive, and highly successful method of parath...

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Main Authors: Ryan Winters, Paul Friedlander, Salem Noureldine, Ibrahim Ekaidi, Krzysztof Moroz, Emad Kandil
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Minimally Invasive Surgery
Online Access:http://dx.doi.org/10.1155/2011/487076
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spelling doaj-6e939b7b510742c0877ff4c22cd649772020-11-24T22:30:43ZengHindawi LimitedMinimally Invasive Surgery2090-14452090-14532011-01-01201110.1155/2011/487076487076Preoperative Parathyroid Needle Localization: A Minimally Invasive Novel Technique in Reoperative SettingsRyan Winters0Paul Friedlander1Salem Noureldine2Ibrahim Ekaidi3Krzysztof Moroz4Emad Kandil5Department of Otolaryngology, Tulane University School of Medicine, New Orleans, LA 70112, USADepartment of Otolaryngology, Tulane University School of Medicine, New Orleans, LA 70112, USADepartment of Surgery, Tulane University School of Medicine, New Orleans, LA 70112, USADepartment of Surgery, Tulane University School of Medicine, New Orleans, LA 70112, USADepartment of Pathology, Tulane University School of Medicine, New Orleans, LA 70112, USADepartment of Otolaryngology, Tulane University School of Medicine, New Orleans, LA 70112, USABackground. Reoperative parathyroid surgery for primary hyperparathyroidism can be challenging. Numerous preoperative localization techniques have been employed to facilitate a more focused surgical exploration. This paper describes a novel, minimally invasive, and highly successful method of parathyroid localization. Methods. Patients with recurrent or persistent primary hyperparathyroidism underwent parathyroidectomy following CT scan or ultrasound-guided wire localization of the parathyroid. Accurate placement was confirmed by fine-needle aspiration with immunocytochemistry or PTH washout. The guide wire was left in situ to guide surgical excision of the gland. Curative resection was established by monitoring intact serum PTH levels after excision of the adenoma. Results. All ten patients underwent successful redo-targeted parathyroidectomy. Nine of the ten patients were discharged on the day of surgery. One patient was observed overnight due to transient postoperative hypocalcemia, which resolved with calcium supplementation. Conclusion. Placement of a localization wire via preoperative high-resolution ultrasound or CT can expedite reoperative parathyroid surgery. It allows identification of parathyroid adenoma via a minimally invasive approach, especially in cases where a sestamibi scan is inconclusive.http://dx.doi.org/10.1155/2011/487076
collection DOAJ
language English
format Article
sources DOAJ
author Ryan Winters
Paul Friedlander
Salem Noureldine
Ibrahim Ekaidi
Krzysztof Moroz
Emad Kandil
spellingShingle Ryan Winters
Paul Friedlander
Salem Noureldine
Ibrahim Ekaidi
Krzysztof Moroz
Emad Kandil
Preoperative Parathyroid Needle Localization: A Minimally Invasive Novel Technique in Reoperative Settings
Minimally Invasive Surgery
author_facet Ryan Winters
Paul Friedlander
Salem Noureldine
Ibrahim Ekaidi
Krzysztof Moroz
Emad Kandil
author_sort Ryan Winters
title Preoperative Parathyroid Needle Localization: A Minimally Invasive Novel Technique in Reoperative Settings
title_short Preoperative Parathyroid Needle Localization: A Minimally Invasive Novel Technique in Reoperative Settings
title_full Preoperative Parathyroid Needle Localization: A Minimally Invasive Novel Technique in Reoperative Settings
title_fullStr Preoperative Parathyroid Needle Localization: A Minimally Invasive Novel Technique in Reoperative Settings
title_full_unstemmed Preoperative Parathyroid Needle Localization: A Minimally Invasive Novel Technique in Reoperative Settings
title_sort preoperative parathyroid needle localization: a minimally invasive novel technique in reoperative settings
publisher Hindawi Limited
series Minimally Invasive Surgery
issn 2090-1445
2090-1453
publishDate 2011-01-01
description Background. Reoperative parathyroid surgery for primary hyperparathyroidism can be challenging. Numerous preoperative localization techniques have been employed to facilitate a more focused surgical exploration. This paper describes a novel, minimally invasive, and highly successful method of parathyroid localization. Methods. Patients with recurrent or persistent primary hyperparathyroidism underwent parathyroidectomy following CT scan or ultrasound-guided wire localization of the parathyroid. Accurate placement was confirmed by fine-needle aspiration with immunocytochemistry or PTH washout. The guide wire was left in situ to guide surgical excision of the gland. Curative resection was established by monitoring intact serum PTH levels after excision of the adenoma. Results. All ten patients underwent successful redo-targeted parathyroidectomy. Nine of the ten patients were discharged on the day of surgery. One patient was observed overnight due to transient postoperative hypocalcemia, which resolved with calcium supplementation. Conclusion. Placement of a localization wire via preoperative high-resolution ultrasound or CT can expedite reoperative parathyroid surgery. It allows identification of parathyroid adenoma via a minimally invasive approach, especially in cases where a sestamibi scan is inconclusive.
url http://dx.doi.org/10.1155/2011/487076
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