Optimization of Atropine Extraction Process from Atropa Belladonna by Modified Bubble Column Extractor with Ultrasonic Bath
Modified Bubble Column Extraction with Ultrasonic Bath (BCE-UB) method was used to extract atropine from the stem and leaves of Atropa belladonna. Optimum condition were obtained with Kamada solvent which was chloroform-methanol-ammonia 15:15:1(v/v/v) as extraction solvent, the particle size of les...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Iranian Institute of Research and Development in Chemical Industries (IRDCI)-ACECR
2016-12-01
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| Series: | Iranian Journal of Chemistry & Chemical Engineering |
| Subjects: | |
| Online Access: | http://www.ijcce.ac.ir/article_23556_c8658b3ac0ad7008631b8e029ae03d22.pdf |
| Summary: | Modified Bubble Column Extraction with Ultrasonic Bath (BCE-UB) method was used to extract atropine from the stem and leaves of Atropa belladonna. Optimum condition were obtained with Kamada solvent which was chloroform-methanol-ammonia 15:15:1(v/v/v) as extraction solvent, the particle size of less than 350 µm, an extraction time of 23.95 min, a liquor to material ratio of 15.08 mL/g and an air flow of 6.31 mL/min.g. In this state, percent of extracted atropine was calculated which was equal to 6.81%. Percent of extracted atropine was 6.31% that showed a little difference compared to the predicted value. In order to study the effect of bubbles on the extraction rate, the same extraction with the previous method was performed in a stirred tank. Percent of atropine was 5.59%. |
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| ISSN: | 1021-9986 1021-9986 |