Analysis of genomic variation in lung adenocarcinoma patients revealed the critical role of PI3K complex

Analysis of genomic variation in lung adenocarcinoma patients revealed the critical role of PI3K complex

Background Molecularly targeted therapies improved survival status of some patients with lung adenocarcinoma, which accounts for 40% of all lung cancers, and in-depth study of gene alterations is important for the personalized treatment. Methods The legacy archive data of clinical information and ge...

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Bibliographic Details
Main Authors: Zhao min Deng, Lin Liu, Wen hai Qiu, Yong qun Zhang, Hong yan Zhong, Ping Liao, Yun hong Wu
Format: Article
Language:English
Published: PeerJ Inc. 2017-05-01
Series:PeerJ
Subjects:
Lung adenocarcinoma
Genomic variation
CNV
Mutations
PI3K
Online Access:https://peerj.com/articles/3216.pdf

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