Doxorubicin Activates Hepatitis B Virus Replication by Elevation of p21 (Waf1/Cip1) and C/EBPα Expression.

Hepatitis B virus reactivation is an important medical issue in cancer patients who undergo systemic chemotherapy. Up to half of CHB carriers receiving chemotherapy develop hepatitis and among these cases a notable proportion are associated with HBV reactivation. However, the molecular mechanism(s)...

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Bibliographic Details
Main Authors: Yu-Fang Chen, Chin-Liew Chong, Yi-Chieh Wu, Yi-Ling Wang, Kuen-Nan Tsai, Tzer-Min Kuo, Ming-Hsiang Hong, Cheng-Po Hu, Mong-Liang Chen, Yu-Chi Chou, Chungming Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4486450?pdf=render