Membrane-Associated, Not Cytoplasmic or Nuclear, FGFR1 Induces Neuronal Differentiation

Membrane-Associated, Not Cytoplasmic or Nuclear, FGFR1 Induces Neuronal Differentiation

The intracellular transport of receptor tyrosine kinases results in the differential activation of various signaling pathways. In this study, optogenetic stimulation of fibroblast growth factor receptor type 1 (FGFR1) was performed to study the effects of subcellular targeting of receptor kinases on...

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Bibliographic Details
Main Authors: Katalin Csanaky, Michael W. Hess, Lars Klimaschewski
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cells
Subjects:
optogenetics
FGF2
ERK
AKT
receptor kinase
neurite outgrowth
HEK293
PC12
Online Access:http://www.mdpi.com/2073-4409/8/3/243

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