A Simple and Robust Method for Establishing Homogeneous Mouse Epiblast Stem Cell Lines by Wnt Inhibition

A Simple and Robust Method for Establishing Homogeneous Mouse Epiblast Stem Cell Lines by Wnt Inhibition

Epiblast stem cells (EpiSCs) are pluripotent stem cells derived from epiblasts of postimplantation mouse embryos, and thus provide a useful model for studying “primed” pluripotent states. Here, we devised a simple and robust technique to derive high-quality EpiSCs using an inhibitor of WNT secretion...

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Bibliographic Details
Main Authors: Michihiko Sugimoto, Masayo Kondo, Yumiko Koga, Hirosuke Shiura, Rieko Ikeda, Michiko Hirose, Atsuo Ogura, Ayumi Murakami, Atsushi Yoshiki, Susana M. Chuva de Sousa Lopes, Kuniya Abe
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115000703

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http://www.sciencedirect.com/science/article/pii/S2213671115000703

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