A Case of Mitral Valve Metastasis From Breast Carcinoma Mimicking as a Mitral Valve Regurgitation

• Main Authors: Aghigh Heidari, Fereidoun Sabzi
• Format: Article
• Language: English
• Published: Tehran University of Medical Sciences 2019-02-01
• Series: Acta Medica Iranica
• Subjects: Breast neoplasm metastasis; Cardiac valve; Tamponade; Pericardial effusion
• Online Access: http://acta.tums.ac.ir/index.php/acta/article/view/6699

Metastatic involvement of cardiac valve and pericardium mimicking a cardiac valve pathology accompanied with cardiac tamponade is a rare phenomenon. These metastases commonly arise from the lymphoreticular system, the pulmonary system, and breast. Metastatic spread of breast carcinoma to the cardiac valve is exceedingly rare, and only two case reports have been detected in English literature so far. We report a rare case of a patient with adenocarcinoma of the breast, which presented with severe mitral valve regurgitation and pericardial effusion which was managed urgently with mitral valve replacement. Our case shows the probability of combined metastatic pericardial and valve involvement in patients with breast adenocarcinoma. The patient was treated with mitral valve replacement and intrapericardial infusion of cisplatinum drug to control possible recurrent effusion.