Deficient dopamine D2 receptor function causes renal inflammation independently of high blood pressure.

Deficient dopamine D2 receptor function causes renal inflammation independently of high blood pressure.

Renal dopamine receptors participate in the regulation of blood pressure. Genetic factors, including polymorphisms of the dopamine D(2) receptor gene (DRD2) are associated with essential hypertension, but the mechanisms of their contribution are incompletely understood. Mice lacking Drd2 (D(2)-/-) h...

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Bibliographic Details
Main Authors: Yanrong Zhang, Santiago Cuevas, Laureano D Asico, Crisanto Escano, Yu Yang, Annabelle M Pascua, Xiaoyan Wang, John E Jones, David Grandy, Gilbert Eisner, Pedro A Jose, Ines Armando
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3375266?pdf=render

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