Functional Implications of Local DNA Structures in Regulatory Motifs
The three-dimensional structure of DNA has been proposed to be a major determinant for functional transcription factors (TFs) and DNA interaction. Here, we use hydroxyl radical cleavage pattern as a measure of local DNA structure. We compared the conservation between DNA sequence and structure in te...
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2013-01-01
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Series: | The Scientific World Journal |
Online Access: | http://dx.doi.org/10.1155/2013/965752 |