Application of <i>In-Situ</i> and Soft-Sensors for Estimation of Recombinant <i>P. pastoris</i> GS115 Biomass Concentration: A Case Analysis of HBcAg (Mut<sup>+</sup>) and HBsAg (Mut<sup>S</sup>) Production Processes under Varying Conditions

Application of <i>In-Situ</i> and Soft-Sensors for Estimation of Recombinant <i>P. pastoris</i> GS115 Biomass Concentration: A Case Analysis of HBcAg (Mut<sup>+</sup>) and HBsAg (Mut<sup>S</sup>) Production Processes under Varying Conditions

Microbial biomass concentration is a key bioprocess parameter, estimated using various labor, operator and process cross-sensitive techniques, analyzed in a broad context and therefore the subject of correct interpretation. In this paper, the authors present the results of <i>P. pastoris </...

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Bibliographic Details
Main Authors: Oskars Grigs, Emils Bolmanis, Vytautas Galvanauskas
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Sensors
Subjects:
biomass concentration
<i>in-situ</i> and soft-sensors
turbidity
permittivity
signal filtering
off-gas analysis
Online Access:https://www.mdpi.com/1424-8220/21/4/1268

Internet

https://www.mdpi.com/1424-8220/21/4/1268

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