Comparative magnitude of cross-strain conservation of HIV variable loop neutralization epitopes.

Although the sequence variable loops of the human immunodeficiency virus' (HIV-1) surface envelope glycoprotein (gp120) can exhibit good immunogenicity, characterizing conserved (invariant) cross-strain neutralization epitopes within these loops has proven difficult. We recently developed a met...

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Bibliographic Details
Main Authors: James Swetnam, Evgeny Shmelkov, Susan Zolla-Pazner, Timothy Cardozo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3012121?pdf=render