Sulforaphane ameliorates cadmium induced hepatotoxicity through the up-regulation of /Nrf2/ARE pathway and the inactivation of NF-κB

Sulforaphane ameliorates cadmium induced hepatotoxicity through the up-regulation of /Nrf2/ARE pathway and the inactivation of NF-κB

This study aimed to assess the ameliorative effect and mechanisms of sulforaphane (SFN) on cadmium (Cd)-induced hepatotoxicity. Four in vitro free radical scavenging tests, HepG2 cell viability analysis, and cadmium chloride (CdCl2) indeced liver injured mice mode were employed. SFN scavenged the fr...

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Bibliographic Details
Main Authors: Qingfeng He, Yunjing Luo, Ziqi Xie
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Journal of Functional Foods
Subjects:
Cadmium
Sulforaphen
Hepatotoxicity
Oxidative stress
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464620305211

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