INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS

INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS

In the children with secondary infective endocarditis, the contents of TNK cells was found to be decreased. Same patients exhibit low concentrations of total IgG and its subclasses, IgG1 and IgG2 subclasses decreased, whereas IgG4 levels are increased. Stimulated phagocytic response is also decrease...

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Main Authors: A. B. Dolina, B. I. Kuznik, V. J Rosenberg, T. M. Vishnyakova, Yu. A. Vitkovsky
Format: Article
Language:Russian
Published: SPb RAACI 2014-07-01
Series:Medicinskaâ Immunologiâ
Subjects:
infectious endocarditis
thymalin
immunity
phagocytosis
lymphocyte/platelet aggregations
Online Access:https://www.mimmun.ru/mimmun/article/view/207
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spelling doaj-6e0d1508be424c15966f06574f0618182021-07-29T09:02:22ZrusSPb RAACIMedicinskaâ Immunologiâ1563-06252313-741X2014-07-01124-538138610.15789/1563-0625-2010-4-5-381-386204INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITISA. B. Dolina0B. I. Kuznik1V. J Rosenberg2T. M. Vishnyakova3Yu. A. Vitkovsky4ГОУ ВПО Читинская государственная медицинская академия, г. ЧитаГОУ ВПО Читинская государственная медицинская академия, г. ЧитаГОУ ВПО Читинская государственная медицинская академия, г. ЧитаГОУ ВПО Читинская государственная медицинская академия, г. ЧитаГОУ ВПО Читинская государственная медицинская академия, г. ЧитаIn the children with secondary infective endocarditis, the contents of TNK cells was found to be decreased. Same patients exhibit low concentrations of total IgG and its subclasses, IgG1 and IgG2 subclasses decreased, whereas IgG4 levels are increased. Stimulated phagocytic response is also decreased in these patients, along with increased numbers of lymphocyte/platelet cell aggregates. Effect of a conventional treatment with addition of thymalin when treating secondary infective endocarditis, was more pronounced, in comparison with conventional therapy, with respect to restoration of humoral immunity, phagocytic activity of leukocytes and lymphocyte-platelet adhesion.https://www.mimmun.ru/mimmun/article/view/207infectious endocarditisthymalinimmunityphagocytosislymphocyte/platelet aggregations
collection DOAJ
language Russian
format Article
sources DOAJ
author A. B. Dolina
B. I. Kuznik
V. J Rosenberg
T. M. Vishnyakova
Yu. A. Vitkovsky
spellingShingle A. B. Dolina
B. I. Kuznik
V. J Rosenberg
T. M. Vishnyakova
Yu. A. Vitkovsky
INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS
Medicinskaâ Immunologiâ
infectious endocarditis
thymalin
immunity
phagocytosis
lymphocyte/platelet aggregations
author_facet A. B. Dolina
B. I. Kuznik
V. J Rosenberg
T. M. Vishnyakova
Yu. A. Vitkovsky
author_sort A. B. Dolina
title INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS
title_short INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS
title_full INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS
title_fullStr INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS
title_full_unstemmed INFLUENCE OF THIMALIN UPON IMMUNITY AND LYMPHOCYTE-PLATELET ADHESION IN CHILDREN WITH SECONDARY INFECTIOUS ENDOCARDITIS
title_sort influence of thimalin upon immunity and lymphocyte-platelet adhesion in children with secondary infectious endocarditis
publisher SPb RAACI
series Medicinskaâ Immunologiâ
issn 1563-0625
2313-741X
publishDate 2014-07-01
description In the children with secondary infective endocarditis, the contents of TNK cells was found to be decreased. Same patients exhibit low concentrations of total IgG and its subclasses, IgG1 and IgG2 subclasses decreased, whereas IgG4 levels are increased. Stimulated phagocytic response is also decreased in these patients, along with increased numbers of lymphocyte/platelet cell aggregates. Effect of a conventional treatment with addition of thymalin when treating secondary infective endocarditis, was more pronounced, in comparison with conventional therapy, with respect to restoration of humoral immunity, phagocytic activity of leukocytes and lymphocyte-platelet adhesion.
topic infectious endocarditis
thymalin
immunity
phagocytosis
lymphocyte/platelet aggregations
url https://www.mimmun.ru/mimmun/article/view/207
work_keys_str_mv AT abdolina influenceofthimalinuponimmunityandlymphocyteplateletadhesioninchildrenwithsecondaryinfectiousendocarditis
AT bikuznik influenceofthimalinuponimmunityandlymphocyteplateletadhesioninchildrenwithsecondaryinfectiousendocarditis
AT vjrosenberg influenceofthimalinuponimmunityandlymphocyteplateletadhesioninchildrenwithsecondaryinfectiousendocarditis
AT tmvishnyakova influenceofthimalinuponimmunityandlymphocyteplateletadhesioninchildrenwithsecondaryinfectiousendocarditis
AT yuavitkovsky influenceofthimalinuponimmunityandlymphocyteplateletadhesioninchildrenwithsecondaryinfectiousendocarditis
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