Valproic Acid-Induced Liver Injury: A Case-Control Study from a Prospective Pharmacovigilance Program in a Tertiary Hospital

Valproic Acid-Induced Liver Injury: A Case-Control Study from a Prospective Pharmacovigilance Program in a Tertiary Hospital

Introduction: Valproic acid (VPA) is an antiepileptic drug extensively used for treating partial and generalised seizures, acute mania and as prophylaxis for bipolar disorder. Drug-induced liver injury (DILI) persists as a significant issue related to fatal outcomes by VPA. The aim of this study was...

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Bibliographic Details
Main Authors: Enrique S. Meseguer, Mikel U. Elizalde, Alberto M. Borobia, Elena Ramírez
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Journal of Clinical Medicine
Subjects:
valproic acid
drug-induced liver injury
adverse drug reaction
case-control study
Online Access:https://www.mdpi.com/2077-0383/10/6/1153

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