The role of serine protease HtrA in acute ulcerative enterocolitis and extra-intestinal immune responses during Campylobacter jejuni infection of gnotobiotic IL-10 deficient mice

The role of serine protease HtrA in acute ulcerative enterocolitis and extra-intestinal immune responses during Campylobacter jejuni infection of gnotobiotic IL-10 deficient mice

Campylobacter jejuni infections have a high prevalence worldwide and represent a significant socioeconomic burden. C. jejuni can cross the intestinal epithelial barrier as visualised in biopsies derived from human patients and animal models, however, the underlying molecular mechanisms and associate...

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Bibliographic Details
Main Authors: Markus M. Heimesaat, Marie eAlutis, Ursula eGrundmann, André eFischer, Nicole eTegtmeyer, Manja eBöhm, Anja A. Kühl, Ulf B. Göbel, Steffen eBackert, Stefan eBereswill
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Bacterial Translocation
Campylobacter jejuni
innate immunity
host cell invasion
colonization resistance
htrA gene
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00077/full

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