Functionally-Impaired HIV-1 Nef Alleles from a Mother-Child Transmission Pair

Functionally-Impaired HIV-1 Nef Alleles from a Mother-Child Transmission Pair

Abstract: Unusual HIV-1 nef alleles were isolated from a woman and her vertically infected child. Both patients eventually progressed to develop AIDS. The child died at age 6.5 years, while the mother is currently alive, 13 years since her diagnosis with HIV-1. Predicted amino acid sequences of both...

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Bibliographic Details
Main Authors: Vincent C. Bond, Michael Powell, Warner C. Greene, Jalal A. Zuberi, Harold G. Stringer, Romas Geleziunas, Mafhuz Khan, William W. Roth
Format: Article
Language:English
Published: MDPI AG 2002-10-01
Series:International Journal of Molecular Sciences
Subjects:
HIV-1
Nef
in vitro
CD4
MHC
infectivity
Online Access:http://www.mdpi.com/1422-0067/3/10/1058/

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