Computational Analysis of POL Gene of Human Immunodeficiency Virus Type 1 (HIV-1)
AIDS results from an infection with HIV-1 virus. It is a class of retrovirus whose genome contains the genes for reverse transcriptase. The gene that codes for reverse transcriptase in HIV-1 is the POL gene. POL genes are found in many retroviruses, including a number that are harbored by human popu...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
AcademicPres
2009-11-01
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| Series: | Notulae Botanicae Horti Agrobotanici Cluj-Napoca |
| Online Access: | http://www.notulaebotanicae.ro/index.php/nbha/article/view/3437 |
| Summary: | AIDS results from an infection with HIV-1 virus. It is a class of retrovirus whose genome contains the genes for reverse transcriptase. The gene that codes for reverse transcriptase in HIV-1 is the POL gene. POL genes are found in many retroviruses, including a number that are harbored by human populations. In this paper POL genes of HIV-1 virus were studied using bioinformatics tools. It was observed that there exists a close resemblance among various strains endemic in Africa, China and India. In addition, they express a wide range of functional proteins after infection. |
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| ISSN: | 0255-965X 1842-4309 |