Effects of AAV-proBDNF on hippocampal DCX positive cells and PSD-95 expression in Alzheimer's disease mice

Objective To explore the effects of lateral ventricle injection of recombinant adeno-associated virus-brain-derived neurotrophic factor precursor (AAV-proBDNF) on the hippocampal neurogenesis in APPswePS1dE9 transgenic mice (Alzheimer's disease, AD). Methods Fifteen APP/PS1 dE9 transgenic mice...

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Bibliographic Details
Main Authors: XU Manyu, CHEN Jia, XU Zhiqiang
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2019-01-01
Series:Di-san junyi daxue xuebao
Subjects:
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/201808088.htm