TAM-derived extracellular vesicles containing microRNA-29a-3p explain the deterioration of ovarian cancer

TAM-derived extracellular vesicles containing microRNA-29a-3p explain the deterioration of ovarian cancer

Extracellular vesicles (EVs) secreted from tumor-associated macrophages (TAMs) are known to generate an immune-suppressive environment conducive to the development of ovarian cancer (OC). We tried to elucidate the role of TAM-derived exosomal microRNA (miR)-29a-3p in OC. miR-29a-3p, forkhead box pro...

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Bibliographic Details
Main Authors: Lili Lu, Wanwen Ling, Zhengyi Ruan
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
tumor-associated macrophage-derived extracellular vesicles
microRNA-29a-3p
forkhead box protein O3
serine/threonine protein kinase/glycogen synthase kinase 3β
programmed death ligand-1
ovarian cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S216225312100127X

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http://www.sciencedirect.com/science/article/pii/S216225312100127X

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