Miro1 Deficiency in Amyotrophic Lateral Sclerosis

Miro1 Deficiency in Amyotrophic Lateral Sclerosis

Proper transportation of mitochondria to sites with high energy demands is critical for neuronal function and survival. Impaired mitochondrial movement has been repeatedly reported in motor neurons of amyotrophic lateral sclerosis (ALS) patients and indicated as an important mechanism contributing t...

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Bibliographic Details
Main Authors:	Fan eZhang, Wenzhang eWang, Sandra eSiedlak, Yingchao eLiu, Jun eLiu, Keji eJiang, George ePerry, Xiongwei eZhu, Xinglong eWang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-05-01
Series:	Frontiers in Aging Neuroscience
Subjects:	mitochondrial transport TDP-43 SOD1 glutamate excitotoxicity Neurodegenration amyloid lateral sclerosis
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00100/full

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