Molecular Mechanisms of the Toll-Like Receptor, STING, MAVS, Inflammasome, and Interferon Pathways
Pattern recognition receptors (PRRs) form the front line of defense against pathogens. Many of the molecular mechanisms that facilitate PRR signaling have been characterized in detail, which is critical for the development of accurate PRR pathway models at the molecular interaction level.
Main Authors: | Nathan P. Manes, Aleksandra Nita-Lazar |
---|---|
Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2021-06-01
|
Series: | mSystems |
Online Access: | https://journals.asm.org/doi/10.1128/mSystems.00336-21 |
Similar Items
-
Both STING and MAVS fish orthologs contribute to the induction of interferon mediated by RIG-I.
by: Stéphane Biacchesi, et al.
Published: (2012-01-01) -
Human cytomegalovirus-encoded US9 targets MAVS and STING signaling to evade type I interferon immune responses
by: Hyun jin Choi, et al.
Published: (2018-01-01) -
HIV and HCV activate the inflammasome in monocytes and macrophages via endosomal Toll-like receptors without induction of type 1 interferon.
by: Michael A Chattergoon, et al.
Published: (2014-05-01) -
Recognition of Double-Stranded RNA and Regulation of Interferon Pathway by Toll-Like Receptor 10
by: Suki Man-Yan Lee, et al.
Published: (2018-03-01) -
Opposing roles of Toll-like receptor and cytosolic DNA-STING signaling pathways for Staphylococcus aureus cutaneous host defense.
by: Philip O Scumpia, et al.
Published: (2017-07-01)