Quaternized chitosan nanoparticles loaded with the combined attenuated live vaccine against Newcastle disease and infectious bronchitis elicit immune response in chicken after intranasal administration

Quaternized chitosan nanoparticles loaded with the combined attenuated live vaccine against Newcastle disease and infectious bronchitis elicit immune response in chicken after intranasal administration

Newcastle disease (ND) and infectious bronchitis (IB) are important diseases, which cause respiratory diseases in chickens, resulting in severely economic losses in the poultry industry. In this study, N-2-hydroxypropyl trimethyl ammonium chloride chitosan (N-2-HACC) and N,O-carboxymethyl chitosan (...

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Bibliographic Details
Main Authors: Kai Zhao, Shanshan Li, Wei Li, Lu Yu, Xutong Duan, Jinyu Han, Xiaohua Wang, Zheng Jin
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Drug Delivery
Subjects:
newcastle disease
infectious bronchitis
n-2-hydroxypropyl trimethyl ammonium chloride chitosan nanoparticles
vaccine adjuvant
intranasal delivery
Online Access:http://dx.doi.org/10.1080/10717544.2017.1388450

Internet

http://dx.doi.org/10.1080/10717544.2017.1388450

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