Fibroblast growth factor receptor 3 in hepatocytes protects from toxin-induced liver injury and fibrosis

Fibroblast growth factor receptor 3 in hepatocytes protects from toxin-induced liver injury and fibrosis

Summary: The liver's remarkable regenerative capacity is orchestrated by several growth factors and cytokines. Fibroblast growth factor receptor 3 (Fgfr3) is frequently overexpressed in hepatocellular carcinoma and promotes cancer aggressiveness, whereas its role in liver homeostasis, repair an...

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Bibliographic Details
Main Authors:	Abbie E. Fearon, Coenraad F. Slabber, Andrii Kuklin, Marc Bachofner, Luigi Tortola, Lea Pohlmeier, Sophia Pantasis, Thorsten Hornemann, Lin Chen, Manfred Kopf, Sabine Werner
Format:	Article
Language:	English
Published:	Elsevier 2021-10-01
Series:	iScience
Subjects:	Biological sciences cell biology molecular biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004221011111

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