Calcium Release from Endoplasmic Reticulum Involves Calmodulin-Mediated NADPH Oxidase-Derived Reactive Oxygen Species Production in Endothelial Cells

Calcium Release from Endoplasmic Reticulum Involves Calmodulin-Mediated NADPH Oxidase-Derived Reactive Oxygen Species Production in Endothelial Cells

Background: Previous studies demonstrated that calcium/calmodulin (Ca<sup>2+</sup>/CaM) activates nicotinamide adenine dinucleotide phosphate oxidases (NOX). In endothelial cells, the elevation of intracellular Ca<sup>2+</sup> level consists of two components: Ca<sup>2+...

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Bibliographic Details
Main Authors: Ryugo Sakurada, Keiichi Odagiri, Akio Hakamata, Chiaki Kamiya, Jiazhang Wei, Hiroshi Watanabe
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
NADPH oxidase
reactive oxygen species
endothelial cell
endoplasmic reticulum
calcium
calmodulin
Online Access:https://www.mdpi.com/1422-0067/20/7/1644

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