Phenotypic modulation of primary vascular smooth muscle cells by short-term culture on micropatterned substrate.

Phenotypic modulation of primary vascular smooth muscle cells by short-term culture on micropatterned substrate.

Loss of contractility and acquisition of an epithelial phenotype of vascular smooth muscle cells (VSMCs) are key events in proliferative vascular pathologies such as atherosclerosis and post-angioplastic restenosis. There is no proper cell culture system allowing differentiation of VSMCs so that it...

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Bibliographic Details
Main Authors: Soyoung Chang, Seungjeong Song, Jungsul Lee, Jonghee Yoon, Junseong Park, Sungyoung Choi, Je-Kyun Park, Kyungsun Choi, Chulhee Choi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3913720?pdf=render

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