Synthesis and Laccase-Mediated Oxidation of New Condensed 1,4-Dihydropyridine Derivatives

Synthesis and Laccase-Mediated Oxidation of New Condensed 1,4-Dihydropyridine Derivatives

We describe herein the synthesis and laccase mediated oxidation of six novel 1,4-dihydropyridine (DHP)-based hexahydroquinolines (DHP1-DHP3) and decahydroacridines (DHP4-DHP6). We employed different laccase enzymes with varying redox potential to convert DHP1-DHP3 and DHP4-DHP6 to the corresponding...

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Bibliographic Details
Main Authors: Jelena Milovanovic, Miyase Gözde Gündüz, Anastasia Zerva, Milos Petkovic, Vladimir Beskoski, Nikolaos S. Thomaidis, Evangelos Topakas, Jasmina Nikodinovic-Runic
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Catalysts
Subjects:
dihydropyridine
hexahydroquinoline
acridinedione
laccase
biotransformation
Online Access:https://www.mdpi.com/2073-4344/11/6/727

Internet

https://www.mdpi.com/2073-4344/11/6/727

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