Characterisation of a peripheral neuropathic component of the rat monoiodoacetate model of osteoarthritis.

Characterisation of a peripheral neuropathic component of the rat monoiodoacetate model of osteoarthritis.

Joint degeneration observed in the rat monoiodoacetate (MIA) model of osteoarthritis shares many histological features with the clinical condition. The accompanying pain phenotype has seen the model widely used to investigate the pathophysiology of osteoarthritis pain, and for preclinical screening...

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Bibliographic Details
Main Authors: Matthew Thakur, Wahida Rahman, Carl Hobbs, Anthony H Dickenson, David L H Bennett
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3312347?pdf=render

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