| Summary: | <p>Sarcoidosis is a multi-system disease of unknown causes development. Aim: study of the level of progesterone blood of patients with sarcoidosis, depending on their gender. <em>Materials and methods:</em> a defined level of progesterone blood serum in 71 patients with newly diagnosed with sarcoidosis aged 20 to 65 years. <em>Results:</em> comparing indices of progesterone 31st men with respiratory sarcoidosis and the control group was discovered a higher level of progesterone among patients. Depending on the indications to the treatment with glucocorticoids were also found statistically significant differences. The analysis of progesterone blood in patients with sarcoidosis in the reproductive age is statistically significant difference between the level of progesterone in women, which the recommended therapy with glucocorticosteroids, and who is not. The first group he significantly lower than in the second group, as well as reduced as compared with a control group of healthy women. When studying the level of progesterone in the patients in the period of menopause, which is not recommended by hormone therapy, indicators are statistically significantly higher in comparison with the control group, consisting of healthy postmenopausal women age (p<0.05). <em>Conclusion</em>: the necessity of detailed studying of the state of sexual hormones to treat sarcoidosis and the background of the different regimens.</p><p><strong>DOI: <a href="http://dx.doi.org/10.12731/2218-7405-2014-2-4">http://dx.doi.org/10.12731/2218-7405-2014-2-4</a></strong></p>
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