Computational prediction of changes in brain metabolic fluxes during Parkinson's disease from mRNA expression.

BACKGROUND:Parkinson's disease is a widespread neurodegenerative disorder which affects brain metabolism. Although changes in gene expression during disease are often measured, it is difficult to predict metabolic fluxes from gene expression data. Here we explore the hypothesis that changes in...

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Bibliographic Details
Main Authors: Farahaniza Supandi, Johannes H G M van Beek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6135490?pdf=render