Rationally designed Human Cytomegalovirus gB nanoparticle vaccine with improved immunogenicity.
Human cytomegalovirus (HCMV) is the primary viral cause of congenital birth defects and causes significant morbidity and mortality in immune-suppressed transplant recipients. Despite considerable efforts in vaccine development, HCMV infection still represents an unmet clinical need. In recent phase...
Main Authors: | Michela Perotti, Jessica Marcandalli, Davide Demurtas, Federica Sallusto, Laurent Perez |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-12-01
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Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1009169 |
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