Revised Exon Structure of l-DOPA Decarboxylase (<i>DDC</i>) Reveals Novel Splice Variants Associated with Colorectal Cancer Progression

Revised Exon Structure of l-DOPA Decarboxylase (<i>DDC</i>) Reveals Novel Splice Variants Associated with Colorectal Cancer Progression

Colorectal cancer (CRC) is a highly heterogenous malignancy with an increased mortality rate. Aberrant splicing is a typical characteristic of CRC, and several studies support the prognostic value of particular transcripts in this malignancy. l-DOPA decarboxylase (DDC) and its derivative neurotransm...

Full description

Bibliographic Details
Main Authors: Pinelopi I. Artemaki, Maria Papatsirou, Michaela A. Boti, Panagiotis G. Adamopoulos, Spyridon Christodoulou, Dido Vassilacopoulou, Andreas Scorilas, Christos K. Kontos
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
l-aromatic amino acid decarboxylase (AADC)
next-generation sequencing (NGS)
transcriptomics
alternative splicing
protein isoforms
colon carcinoma
Online Access:https://www.mdpi.com/1422-0067/21/22/8568

Internet

https://www.mdpi.com/1422-0067/21/22/8568

Similar Items