Oral Squamous Cell Carcinoma in a Patient with Fanconi Anemia

Oral Squamous Cell Carcinoma in a Patient with Fanconi Anemia

Fanconi anemia (FA) is a rare autosomal recessive genetic disorder characterized by different types of malformations, skin lesions, bone marrow failure, and increased risk for both hematological malignancies and solid tumors, especially head and neck squamous cell carcinomas (HNSCC). FA patients may...

Full description

Bibliographic Details
Main Authors: Milla Huuhka, Aaro Turunen
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Case Reports in Dentistry
Online Access:http://dx.doi.org/10.1155/2021/5571649
id doaj-6d51e0a6472e4de3a324e1cf734a5682
record_format Article
spelling doaj-6d51e0a6472e4de3a324e1cf734a56822021-07-05T00:02:08ZengHindawi LimitedCase Reports in Dentistry2090-64552021-01-01202110.1155/2021/5571649Oral Squamous Cell Carcinoma in a Patient with Fanconi AnemiaMilla Huuhka0Aaro Turunen1Department of Oral and Maxillofacial DiseasesDepartment of Oral and Maxillofacial DiseasesFanconi anemia (FA) is a rare autosomal recessive genetic disorder characterized by different types of malformations, skin lesions, bone marrow failure, and increased risk for both hematological malignancies and solid tumors, especially head and neck squamous cell carcinomas (HNSCC). FA patients may also display a low tolerance to oncologic treatments. The authors present a case of mandibular squamous cell carcinoma in a young FA patient. Because of the aggressive nature of the SCC and complex treatment options, we recommend a strict lifelong follow-up for all FA patients to detect early changes in the oral mucosa.http://dx.doi.org/10.1155/2021/5571649
collection DOAJ
language English
format Article
sources DOAJ
author Milla Huuhka
Aaro Turunen
spellingShingle Milla Huuhka
Aaro Turunen
Oral Squamous Cell Carcinoma in a Patient with Fanconi Anemia
Case Reports in Dentistry
author_facet Milla Huuhka
Aaro Turunen
author_sort Milla Huuhka
title Oral Squamous Cell Carcinoma in a Patient with Fanconi Anemia
title_short Oral Squamous Cell Carcinoma in a Patient with Fanconi Anemia
title_full Oral Squamous Cell Carcinoma in a Patient with Fanconi Anemia
title_fullStr Oral Squamous Cell Carcinoma in a Patient with Fanconi Anemia
title_full_unstemmed Oral Squamous Cell Carcinoma in a Patient with Fanconi Anemia
title_sort oral squamous cell carcinoma in a patient with fanconi anemia
publisher Hindawi Limited
series Case Reports in Dentistry
issn 2090-6455
publishDate 2021-01-01
description Fanconi anemia (FA) is a rare autosomal recessive genetic disorder characterized by different types of malformations, skin lesions, bone marrow failure, and increased risk for both hematological malignancies and solid tumors, especially head and neck squamous cell carcinomas (HNSCC). FA patients may also display a low tolerance to oncologic treatments. The authors present a case of mandibular squamous cell carcinoma in a young FA patient. Because of the aggressive nature of the SCC and complex treatment options, we recommend a strict lifelong follow-up for all FA patients to detect early changes in the oral mucosa.
url http://dx.doi.org/10.1155/2021/5571649
work_keys_str_mv AT millahuuhka oralsquamouscellcarcinomainapatientwithfanconianemia
AT aaroturunen oralsquamouscellcarcinomainapatientwithfanconianemia
_version_ 1721319490617081856

Similar Items