CD-Markers as an immunological aspect in patients with visceral leishmaniasis

• Main Authors: Jabbar R. Zangor Al-Autabbi, Zainab A. Hamed. Al-Rubayee
• Format: Article
• Language: English
• Published: Faculty of Medicine University of Baghdad 2010-01-01
• Series: مجلة كلية الطب
• Subjects: CD-Markers profile, leishmania donovani, amastigote form
• Online Access: http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1096

Back ground: Visceral leishmaniasis is an endemic protozoan disease in Iraq. Recovery from this disease confers a solid and permanent immunity. Immunological assessment of our patients was carried out and the results showed a significant reduction in the percentage of CD3, CD56 and a significant increase in the percentage of CD19 in the peripheral blood lymphocyte of VL in comparison with control group. Patients and methods: Indirect immunofluorescence technique analysis was performed to detect the percentage of CD3, CD19and CD56 positive lymphocytes. Results: Our results in the patients groups showed decrease in the percentage of CD3, CD56 and increase in the percentage of CD19. Follow up of patients after treatment showed a significant increase in the percentage of CD3, CD56, but they were still lower than their normal range . Conclusion:- CD3,CD56, were decreased in VL infection then increased after treatment but it was less than its normal range, while CD19 was increased in VL when compared with control group.