CK1α overexpression correlates with poor survival in colorectal cancer

CK1α overexpression correlates with poor survival in colorectal cancer

Abstract Background Colorectal cancer (CRC) is the fourth leading cause of cancer related deaths worldwide and prognosis in advanced tumor stage still remains poor. Since CK1 isoforms have been reported to be deregulated in several tumor entities CK1 has emerged as a novel drug target in cancer ther...

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Bibliographic Details
Main Authors: Julia Richter, Anna-Laura Kretz, Johannes Lemke, Michael Fauler, Jens-Uwe Werner, Stephan Paschke, Frank Leithäuser, Doris Henne-Bruns, Andreas Hillenbrand, Uwe Knippschild
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Cancer
Subjects:
Casein kinase 1 alpha
Biomarker
Colorectal cancer (CRC)
Survival
Prognosis
Drug target
Online Access:http://link.springer.com/article/10.1186/s12885-018-4019-0

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