Circulating matrix metalloproteinase MMP-9 and MMP-2/TIMP-2 complex are associated with spontaneous early pregnancy failure

Circulating matrix metalloproteinase MMP-9 and MMP-2/TIMP-2 complex are associated with spontaneous early pregnancy failure

<p>Abstract</p> <p>Background</p> <p>Trophoblast cell (CTB) invasion into the maternal endometrium plays a crucial role during human embryo implantation and placentation. This invasion is facilitated by the activity of matrix metalloproteinases, which are regulated by t...

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Bibliographic Details
Main Authors: Nissi Ritva, Talvensaari-Mattila Anne, Kotila Vesa, Niinimäki Maarit, Järvelä Ilkka, Turpeenniemi-Hujanen Taina
Format: Article
Language:English
Published: BMC 2013-01-01
Series:Reproductive Biology and Endocrinology
Subjects:
MMP-2
MMP-9
TIMP-1
TIMP-2
Pregnancy
Pregnancy loss
Serum marker
Placentation
Online Access:http://www.rbej.com/content/11/1/2

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