The Hepatitis E Virus Open Reading Frame 2 Protein: Beyond Viral Capsid

The Hepatitis E Virus Open Reading Frame 2 Protein: Beyond Viral Capsid

Hepatitis E virus (HEV) is a zoonotic pathogen causing hepatitis in both human and animal hosts, which is responsible for acute hepatitis E outbreaks worldwide. The 7.2 kb genome of the HEV encodes three well-defined open reading frames (ORFs), where the ORF2 translation product acts as the major vi...

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Bibliographic Details
Main Authors: Zhaobin Zhou, Yinqian Xie, Chunyan Wu, Yuchen Nan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Microbiology
Subjects:
hepatitis E virus
HEV-ORF2 protein
capsids
innate immunity
subunit vaccine
quasi-enveloped virion
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.739124/full

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