Characterization of a fusion protein of RGD4C and the ß-lactamase variant for antibody-directed enzyme prodrug therapy

Xiaoliang Zhou, Hao Wang, Peiji Shi, Ai-min MengInstitute of Radiation Medicine, Tianjin Key Laboratory of Molecular Nuclear Medicine, Tianjin, People's Republic of ChinaAbstract: Antibody-directed enzyme prodrug therapy (ADEPT) delivers chemotherapeutic agents in high concentration to tumo...

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Bibliographic Details
Main Authors: Zhou XL, Wang H, Shi PJ, Meng AM
Format: Article
Language:English
Published: Dove Medical Press 2014-04-01
Series:OncoTargets and Therapy
Online Access:http://www.dovepress.com/characterization-of-a-fusion-protein-of-rgd4c-and-the-szlig-lactamase--a16425