lncRNA H19 promotes matrix mineralization through up-regulating IGF1 by sponging miR-185-5p in osteoblasts

lncRNA H19 promotes matrix mineralization through up-regulating IGF1 by sponging miR-185-5p in osteoblasts

Abstract Background Matrix mineralization is a key stage in bone formation involving in many bone-specific genes and signaling pathways. Emerging evidence indicate that long non-coding RNA (lncRNA) and microRNAs (miRNAs) play crucial roles in regulating the mineralization process of osteoblasts. Thi...

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Bibliographic Details
Main Authors: Yuan Wu, Yu Jiang, Qiang Liu, Cui-Zhong Liu
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Molecular and Cell Biology
Subjects:
lncRNA H19
miR-185-5p
IGF1
Osteoblasts
Mineralization
Online Access:http://link.springer.com/article/10.1186/s12860-019-0230-3

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